The Landsby, Merrion Ave, Stanmore. HA7 4RY Monday–Friday, 3:00 pm–8:00 pm; Saturday, 8:00 am–1:00 pm
Non-surgical knee osteoarthritis treatment

Arthrosamid® Knee Injection for Osteoarthritis Pain

Arthrosamid® is a single injection for knee osteoarthritis that helps cushion the joint from within. Clinical studies have reported sustained improvements in pain and function for up to five years, although individual results can vary.

Arthrosamid injection pack and pre-filled syringe
Clinician holding a pre-filled Arthrosamid syringe, ready for injection

What Is Arthrosamid®?

Arthrosamid® is an injectable hydrogel used to help reduce pain associated with knee osteoarthritis. A single injection is placed into the knee joint, where the hydrogel integrates with the synovial tissue and helps cushion the joint.

Treatment is carried out under local anaesthetic, and you can usually leave the clinic the same day. Clinical studies have reported sustained improvements in knee osteoarthritis symptoms for up to five years after a single injection, although individual results can vary.

  • Clinical studies report sustained improvement for up to five years
  • Improves joint function & mobility
  • Non-degradable, doesn't break down over time
  • Minimally invasive, a single injection
  • Well tolerated in clinical studies
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How Arthrosamid® Works

See how Arthrosamid® works within the knee joint to help reduce osteoarthritis pain and support improved movement.

Illustration of an Arthrosamid injection being administered into the knee joint

How Is Arthrosamid® Administered?

Before the injection, the area around your knee is numbed with local anaesthetic. Antibiotics are also given beforehand to help reduce the risk of infection. At Physivity, ultrasound guidance is used to help confirm accurate placement of the injection within the knee joint.

  • Ultrasound-guided accuracyLive imaging confirms correct placement within the joint capsule during the injection.
  • Same-day procedureYou can usually leave the clinic shortly after treatment, although strenuous activity should be avoided during the first few weeks.

Is Arthrosamid® Right for Me?

Arthrosamid® may be considered for people with knee osteoarthritis who are looking for a non-surgical option to help manage their symptoms. Suitability is assessed following a consultation and review of your medical history, certain medical conditions, infections, previous knee procedures, medications and planned dental or surgical treatment may affect whether Arthrosamid® is appropriate for you. The clinician will discuss the potential benefits, risks and alternatives before treatment.

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When Might I Notice a Difference?

Everyone responds differently. Some people may notice an improvement relatively quickly, while for others the benefits develop gradually. Clinical information indicates that maximum benefit can take around four to twelve weeks.

4–12Weeks

Typical time reported for maximum benefit to develop, based on clinical information.

Still have questions about Arthrosamid®? Speak to our team before you decide.

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What to Expect After Treatment

Most patients tolerate the injection well. Here's what's normal in the days that follow.

Right After Treatment

  • Leave the clinic straight away, or rest first if you prefer
  • Some people experience mild discomfort as the local anaesthetic wears off
  • The joint may feel slightly different due to Arthrosamid®'s thicker consistency

In the Days That Follow

  • Continue your regular medication, including pain relief, as normal
  • Temporary pain or swelling can occur following treatment

Getting Back to Everyday Activity

You may be able to leave the clinic shortly after your injection. As with other invasive joint procedures, strenuous activities such as jogging, tennis and long walks should generally be avoided during the first few weeks. The clinician can advise you on gradually returning to activity and whether structured rehabilitation may be helpful.

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